Sjogren's disease (BS) is a systemic autoimmune disease, the main symptoms of which are associated with dry eyes, mouth, skin, respiratory and gastrointestinal tract, etc., but there are a large number of extra-vascular symptoms that can accompany this disease: weakness, swelling of the lymph nodes, respiratory failure, pain and swelling of the joints, rash, dysphagia, gastro-esophageal reflux, lymphoma, etc. In addition, the etiology of this disease remains unknown, and the pathogenesis is partially studied. The diagnosis of Sjogren's disease is complicated by a variety of clinical manifestations, as well as subacute and chronic variants of the course of the disease, in addition, the diagnostic criteria are periodically changed. It is recommended to adhere to the domestic diagnostic criteria considering the presence of laboratory signs of an autoimmune disease. The article presents a clinical observation of a patient with the development of the main symptoms and signs of BS and autoimmune hepatitis for 20 years. Recurrent mumps or chronic bilateral enlargement of the parotid salivary glands may be the first symptom of Sjogren's disease, which is recommended to extend the examination in order to identify other, sometimes latent signs of the disease.
Sjogren's Syndrome , Humans , Liver , Sjogren's Syndrome/complications , Sjogren's Syndrome/diagnosis
Over the past decades, a small yet convincing evidence base has accumulated that demonstrates the effectiveness of dental care for patients in health-resort (HR) settings. In addition to a positive local effect, complex HR care increases nonspecific resistance and promotes desensitization. OBJECTIVE OF THE REVIEW: Addressing the HR rehabilitation in patients with various maxillofacial diseases for further consideration of the possibility of the increased use of HR care in dental practice. MATERIAL AND METHODS: Russian and English-language publications were analyzed without specifying the search timeframe. The search keywords were the following: «health-resort care¼, «balneotherapy¼, «peloid therapy¼, «physiotherapy¼, «magnet therapy¼, «laser therapy¼ in combination with «dental diseases¼, «maxillofacial diseases¼, «periodontal diseases¼, «temporomandibular joint diseases¼, «postoperative rehabilitation¼ «balneotherapy¼, «mud therapy¼, «peloid therapy¼, «spa therapy¼, «physiotherapy¼. A total of 21 articles were analyzed, including 10 related to periodontal disease, 5 to temporomandibular joint pathology, and 6 to rehabilitation in the postoperative period. Seventeen original studies (3855 patients) were selected, including 47.62% with evidence level C, due to lack of information on comparison group or randomization. RESULTS AND DISCUSSION: Available data from clinical studies suggest the effectiveness of natural and physiotherapeutic factors in the medical rehabilitation of patients with various dental diseases. Further randomized clinical trials and the development of clinical guidelines for various techniques in dental diseases are warranted.
Balneology , Low-Level Light Therapy , Mud Therapy , Dental Care , Health Resorts , Humans
THE AIM OF THE STUDY: Was to conduct an experimental study of the bearing capacity and determination of the Young's modulus of lyophilized allogeneic bone material. MATERIALS AND METHODS: The study used 5 prototypes of lyophilized allogeneic bone blocks, which were alternately subjected to static loading by compressive force. The experimental values of Young's modulus of all bone samples were determined. When applying the Student's probability distribution in statistical processing of experimental data, the average indicators of the forces of destruction of the samples were obtained and Young's modulus was determined. RESULTS AND DISCUSSION: As a result of the study, the indices of the maximum loading (6012H) and Young's modulus (147.2±0.228 MPa) of lyophilized allogeneic bone material were obtained. CONCLUSION: The obtained Young's modulus of lyophilized allogeneic bone material is of great importance in scientific activity, providing the possibility of further investigation of the properties of lyophilized allogeneic bone tissue to form a preoperative forecast of the behavior of an osteoplastic material and a dental implant installed in it.
Bone and Bones , Hematopoietic Stem Cell Transplantation , Elastic Modulus , Humans
The state of the nasal cavity, especially the region of the osteomyomatic complex, plays a significant role in the development of chronic maxillary sinusitis. Odontogenic maxillary sinusitis, as a complication of dental implantological treatment on the upper jaw, is increasingly common. The aim of the study was to increase the effectiveness of prophylaxis and treatment of odontogenic purulent upper jaw sinusitis during reconstructive operations on the alveolar region of the upper jaw. 3 groups of patients were examined: before dental treatment, after dental treatment in the development of odontogenic maxillary sinusitis and 30 patients were selected and examined, who underwent reconstructive surgeries on the alveolar process of the upper jaw and in whom the postoperative period was without complications. The diagnoses of 1st and 2nd group patients required surgical treatment. FESS allows restoring the physiological aeration of maxillary sinuses as naturally as possible, which is important for correct reparative bone regeneration in the alveolar region of maxilla.
Maxillary Sinusitis/surgery , Plastic Surgery Procedures , Humans , Maxilla , Maxillary Sinus/surgery , Postoperative Period
The article presents the analysis of possible options of dental implant surgical treatment of partially edentulous patients with insufficient alveolar bone volume in the period from 2008 to 2017 (n=1004). Highlighted are three main options for surgical treatment: a staged approach, including alveolar ridge augmentation, subsequent dental implantation (n=562); dental implantation with simultaneous alveolar ridge augmentation (n=362); using of 'narrow/short' dental implants (n=80). The data on the frequency of intra - and postoperative complications before prosthetics are given. Over the past period, there has been a declining tendency in the number of staged procedures with an increase in the number of simultaneous operations installations of 'narrow/short' implants.
Alveolar Bone Loss , Alveolar Ridge Augmentation , Dental Implantation, Endosseous , Dental Implants , Jaw, Edentulous, Partially , Bone Transplantation , Humans
The aim of the study was to assess the stress-strain state of «short dental implant - lower jaw bone tissue¼ system in the its osseointegration area under different stress options, of an experimentally developed bone tissue model. Using the finite element analysis method, we investigated a three-dimensional model of an implant with 5.0 mm diameter and 6.5 mm height integrated into the quasi-elastic model of the lower jaw segment with a total deformation modulus of 14 400 MPa and a Poisson's ratio of 0.24 for the cortical layer, for the spongy layer, the general deformation module of 0.2 MPa, Poisson's ratio 0.4. The values of equivalent stresses according to the Genki-Mises criterion for the implant body amounted to 50-76 MPa in the cervical region from the end and inner sides of the implant interface and along the upper edges of the thread edges in the upper third of the implant. Minimum values of 0.1-20 MPa are distributed over the implant body from its cervical part to the top in the lower 2/3. The equivalent von Mises stresses in the bone at the joints of the threaded implant part are minimal - 5-15 MPa. Values of shear stresses in the bone - 2 - 3 MPa, normal vertical stresses - up to 5-13MPa, main tensile stresses - up to 20 MPa, compressive stresses - up to 30-40 MPa. Thus, installing this implant in such model, should not occur irreversible deformations. In our opinion, the structural stability is ensured by the bone tissue features architectonics within 3 mm of the cortical layer, where the maximum stress is redistributed in the future throughout the cortical bone, which can expand the indications for short dental implants use, especially in patients with a limited alveolar bone volume.
Dental Implants , Biomechanical Phenomena , Computer Simulation , Dental Prosthesis Design , Dental Stress Analysis , Finite Element Analysis , Humans , Mandible , Stress, Mechanical
The article presents clinical case of a patient with partial secondary absence of teeth and maxillary defect because of vertical alveolar bone atrophy. Vertical alveolar ridge augmentation by osseous flap rotation and xenogenous bone block with 10% collagen was performed. Eight months later 4 dental implants with modified surface were placed in the augmentation area. After 3 months 3 implants showed no signs of osteointegration and were removed. Three week later the patient was admitted to ENT department because of maxillary sinusitis symptoms.
Alveolar Bone Loss , Alveolar Ridge Augmentation , Dental Implants , Osseointegration , Bone Transplantation , Dental Implantation, Endosseous , Follow-Up Studies , Humans , Maxilla , Maxillary Sinus , Rotation
The method of mathematical planning of sandwich bone plasty is proposed. Displacement level of the bone flap is calculated in advance with regard to prosthetics size, shape and position as well as occlusal relationships. This makes it possible to accurately simulate the bone "basis" improving the prognosis of dental implantation.
Alveolar Ridge Augmentation , Bone and Bones/surgery , Mathematical Computing , Periosteum/surgery , Planning Techniques , Surgical Flaps , Adult , Female , Humans , Male , Middle Aged
An experimental and clinical study was carried out on 76 patients with implant-supported restorations in the posterior zones of the lower jaw, divided in two groups (with no signs of bone resorption around the implants and with resorption signs) and one control group. The results of the study allowed optimizing the angulation of dental implants, providing an opportunity for individual positioning of dental implant in the mandible depending on the direction of functional load.
Dental Arch/surgery , Dental Implants , Dental Occlusion , Dental Prosthesis Design/methods , Dental Prosthesis, Implant-Supported , Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult
Results of the experimental study of material on the bases of bone undemineralized collagen saturated by sulphated glycosaminoglycans are described in the article. It was done in the experiment evaluation of its biocompatibility with surrounding tissues of the experimental animals. On the grounds of the received data it can be concluded that such material implantation into the bone defects would favour quick cell migration into the defect and implant's vascularization, that in its turn would create preconditions for new bone tissue development.
Sulfotransferases/metabolism , Biocompatible Materials , Bone Demineralization Technique , Bone Development/physiology , Bone Matrix/pathology , Bone Substitutes/metabolism , Bone and Bones/cytology , Bone and Bones/metabolism , Humans , Implants, Experimental
Analysis of changes in immunological and biochemical parameters in patients operated on for congenital deformations of the jaw bones and improperly grown fractures showed that postoperative therapy including hyperbaric oxygenation sessions was conducive to increase of immunological reactivity in patients with initially reduced immunological reactivity. No changes in urinary excretion of hydroxyproline were observed in the patients with deformations of the jaws.
Fractures, Malunited/immunology , Hyperbaric Oxygenation , Jaw Abnormalities/immunology , Jaw Fractures/immunology , Adolescent , Adult , Biomarkers/analysis , Cleft Lip/immunology , Cleft Lip/metabolism , Cleft Lip/therapy , Cleft Palate/immunology , Cleft Palate/metabolism , Cleft Palate/therapy , Female , Fractures, Malunited/metabolism , Fractures, Malunited/therapy , Humans , Jaw Abnormalities/metabolism , Jaw Abnormalities/therapy , Jaw Fractures/metabolism , Jaw Fractures/therapy , Male , Postoperative Period , Time Factors
This paper describes a combined theoretical and experimental approach to understanding the capillary spark discharge with specific application to use as a soft x-ray or extreme ultraviolet laser source. Atomic physics calculations have identified several potential laser lines in a collisionally pumped neon-like or nickel-like plasma, and magnetohydrodynamic (MHD) modeling has shown that a capillary discharge device should be capable of producing the correct plasma conditions to achieve a population inversion in some of these lines. An experiment is constructed to evaluate the accuracy of the MHD model and investigate the potential of observing inversion in a neon-like argon or a nickel-like krypton plasma.
Analysis of changes in the immunologic and biochemical parameters in the patients operated on for congenital deformations of the maxillary bones and poorly joined fractures has shown an increase of the immunologic reactivity under the effect of hyperbaric oxygenation therapy administered after surgery to patients with initially reduced levels of these parameters. Urinary excretion of hydroxyproline was found unchanged in patients with maxillary deformations.
Hyperbaric Oxygenation , Jaw Abnormalities/therapy , Adolescent , Adult , Combined Modality Therapy , Female , Fractures, Malunited/immunology , Fractures, Malunited/metabolism , Fractures, Malunited/therapy , Humans , Jaw Abnormalities/immunology , Jaw Abnormalities/metabolism , Male , Mandibular Fractures/immunology , Mandibular Fractures/metabolism , Mandibular Fractures/therapy , Maxillary Fractures/immunology , Maxillary Fractures/metabolism , Maxillary Fractures/therapy , Postoperative Care , Time Factors
